I've only visited Portugal on holiday, I've never been on a rescue so haven't visited any refuges or rescue associations.
Recently I learned about a rescue association in Central Portugal, Louzanimales. This weblink will take you to their website.
This is the story of Louzanimales.
Louzanimales - Association for the Animals of Lousã - was formed by a group of citizens with the mission to defend the rights of animals and, at the same time, reduce the overpopulation of homeless animals in Lousã through sterilization and the development of initiatives that seek their referral for adoption, when their sociability characteristics allow it.
Louzanimales is a 100% voluntary Association, without its own facilities for welcoming animals. It is a group of citizens who offer their contribution to the animal cause.